Enzymes are proficient catalysts that enable fast rates of Michaelis-complex formation, the chemical step and products release. These different steps may require different conformational states of the
Kinetic constants for the hydrolysis of pNPP are included for comparison. Kinetic constants for the hydrolysis of two periplasmic TpbB peptide substrates by TpbA.
CpG methylation is involved in a wide range of biological processes in vertebrates as well as in plants and fungi. To date, three enzymes, Dnmt1, Dnmt3a, and Dnmt3b, are known to have DNA methyltransf
