Effects on the transcriptome of mouse embryonic fibroblasts after both Son overexpression and knockdown and treatment with 3μM nintedanib, 1μM ponatinib, 3μM proflavine hemisulfate, and 1μM pyrvinium pamoate

Understanding how genetic and pharmacological effects that change nuclear speckle morphology affect the global transcriptome Comparison of gene expression profiles of mouse embroyonic fibroblasts (MEFs) after genetic manipulation of Son or the aforementioned drug treatments