Asymmetric Allylic Alkylation of Isatin-Derived Morita–Baylis–Hillman Carbonates with Nitroalkanes
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A stereoselective allylic alkylation of isatin-derived Morita–Baylis–Hillman (MBH) carbonates with nitroalkanes has been developed. In the presence of 10 mol % β-isocupreidine (β-ICD), 3,3′-disubstituted oxindoles were prepared with moderate diastereoselectivities and excellent enantioselectivities.
创建时间:
2012-08-03



