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Epigenome-wide association study of cocaine use disorder in postmortem human brain tissue

NIAID Data Ecosystem2026-03-14 收录

可卡因使用障碍

表观基因组关联分析

数据链接：

https://www.omicsdi.org/dataset/ega/EGAS00001006826 数据链接链接失效反馈

官方服务：

资源简介：

We aimed to identify cocaine use disorder associated DNA methylation alterations in the Brodmann Area 9 brain region.EGA study EGAS00001006826

应用场景：

创建时间：

2023-01-26

疾病表观遗传学

表观基因组关联分析

Peripheral blood from thirty-four monozygotic twin subjects from the general population (n = 17 twin pairs) was collected for epigenomic analysis via Illumina Infinium HumanMethylation450 Beadchip. Al

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PGS: penalized generalized estimating equations with grid search for epigenome-wide multiple measurement study

表观基因组关联分析

纵向数据分析

Motivation: The need of identifying genetic determinants that disclose the heritability of complex traits as well as pinpoint causative genetic effects in some complex diseases has propelled large-sca

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Additional file 11 of DNA methylation and body mass index from birth to adolescence: meta-analyses of epigenome-wide association studies

表观基因组关联分析

肥胖表观遗传学

Additional file 11: Table S9. Results of enrichment analyses for CpGs associated with BMI in previously reported large EWAS (N≥1000).

Figshare2024-02-13 更新30

Results of epigenome wide association of hearing PC1 for discovery and replication samples and their meta-analysis.

表观基因组关联分析

听力表观遗传学

The ten most highly associated differentially methylated regions in the discovery EWAS (27 k) are shown. Probes are characterised by the nearest gene, the association effect (beta), standard error of

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Levels of genomic inflation (Lambda) for each EWAS comparison after correcting for confounders including cell counts.

表观基因组关联分析

遗传统计质量控制

Levels of genomic inflation (Lambda) for each EWAS comparison after correcting for confounders including cell counts.

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