Objective : Previous studies have verified that silent information regulator 1 (SIRT1), a class III histone deacetylase, protects against ischemia reperfusion (IR) injury (IRI) in some organs. I
Data are expressed as the mean ± standard error (n = 6/group). I/R, ischaemia/reperfusion. *p#pMean area at risk and infarct area in rats in the different experimental groups.
Ischemic stroke is characterized by insufficient blood supply to brain tissue and is associated with increased morbidity and mortality in adults worldwide. Growth arrest-specific protein 6 (GAS6) is a