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Loss of Ezh2 synergizes with JAK2-V617F in initiating myeloproliferative neoplasms and promoting myelofibrosis

NIAID Data Ecosystem2026-03-13 收录

骨髓增殖性肿瘤分子机制

纤维化研究

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE82074 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2021-11-17

基因表达调控

纤维化研究

Idiopathic pulmonary fibrosis (IPF) is a progressive and life-threatening respiratory disease characterized by worsening lung function due to excessive scarring. The objective of this study was to inv

DataCite Commons2024-11-29 更新120

JAK2 V617F-Dependent Upregulation of PU.1 Expression in the Peripheral Blood of Myeloproliferative Neoplasm Patients

骨髓增殖性肿瘤分子机制

JAK-STAT信号通路调控

Myeloproliferative neoplasms (MPN) are multiple disease entities characterized by clonal expansion of one or more of the myeloid lineages (i.e. granulocytic, erythroid, megakaryocytic and mast cell).

NIAID Data Ecosystem100

Expression of Autophagy Genes in Myeloproliferative Disorders

骨髓增殖性肿瘤分子机制

自噬基因表达

Comparison of ATG gene family members in MPN pattients with normal controls One-Way ANOVA while contrasting ATG gene family members in 11 Normal (Control) with either 1) 13 PV samples 2) 24 ET sample

NIAID Data Ecosystem50

Fibrosis from Suppression of the TGF-β pathway by a macrolide antibiotic decreases fibrotic responses by ocular fibroblasts in vitro

生物信息学

纤维化研究

The networks filtered by the FocusHeuristics, for fibrosis, including the gene expression data mapped onto these.

DataCite Commons2020-09-24 更新100

The Database of Predictive Targets of miRNA let-7b.zip

miRNA靶标预测

纤维化研究

We filtered let-7b binding sites in the 3'UTRs of transcripts encoding proteins involved in fibrogenesis in Mø using online RNA databases. Briefly, we intersected the top 100 most reliable target gene

DataCite Commons2025-05-01 更新80

Loss of Ezh2 synergizes with JAK2-V617F in initiating myeloproliferative neoplasms and promoting myelofibrosis

资源简介：

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