AJP_Supplementary_data

Figshare2019-12-04 更新2026-04-08 收录

胰岛素分泌机制

脂质信号传导

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Sphingosine-1-phosphate as a key player of insulin secretion induced by high density lipoprotein treatment_supplementary_data

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2019-12-04

Lipolysis regulates major transcriptional programs in brown adipocytes [DOX exp]

脂质信号传导

棕色脂肪细胞转录

β-Adrenergic signaling is a core regulator of brown adipocyte function stimulating both lipolysis and transcription of thermogenic genes, thereby expanding the capacity for oxidative metabolism. Here

NIAID Data Ecosystem130

Genome-wide Circadian Control of Transcription at Active Enhancers Regulates Insulin Secretion and Diabetes Risk. Genome-wide Circadian Control of Transcription at Active Enhancers Regulates Insulin Secretion and Diabetes Risk

昼夜节律转录调控

胰岛素分泌机制

The molecular clock is a transcriptional oscillator present in brain and peripheral cells that coordinates behavior and physiology with the solar cycle. Here we reveal that the clock gates insulin sec

NIAID Data Ecosystem50

Essential roles of aspartate aminotransferase 1 and vesicular glutamate transporters in β-cell glutamate signaling for incretin-induced insulin secretion

胰岛素分泌机制

β细胞信号通路

Incretins (GLP-1 and GIP) potentiate insulin secretion through cAMP signaling in pancreatic β-cells in a glucose-dependent manner. We recently proposed a mechanistic model of incretin-induced insulin

Figshare2017-11-02 更新20

Additional file 13 of A heat-sensitive Osh protein controls PI4P polarity

脂质信号传导

细胞极性调控

Fig. 4d Dataset

Figshare2020-03-14 更新70

Dataset for: The thermodynamic basis of glucose stimulated insulin release: a model of the core mechanism.

胰岛素分泌机制

糖尿病代谢模型

A model for glucose sensing by pancreatic β-cells is developed and compared to the available experimental data. The model brings together mathematical representations for the activities of the glucos

NIAID Data Ecosystem40

AJP_Supplementary_data

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