Sex-dependent effects in the aged melanoma tumor microenvironment influence invasion and resistance to targeted therapy. Chhabra et al
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Retinoic acid inhibits tumor-associated mesenchymal stromal cell transformation in melanoma. Retinoic acid inhibits tumor-associated mesenchymal stromal cell transformation in melanoma
Bone marrow mesenchymal stem/stromal cells (BMSCs) can be transformed into tumor-associated MSCs (TA-MSCs) within the tumor microenvironment to facilitate tumor progression. However, the underline mec
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Gene expression analysis of sorted murine B16-F10 melanoma tumor derived endothelial cells
Individualized outcome prediction classifiers were successfully constructed through expression profiling of a total of 8,644 genes in 50 non-small cell lung cancer (NSCLC) cases, which had been consec
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MacroH2A restricts melanoma progression via inhibition of chemokine expression in cancer-associated fibroblasts [RNA-seq]. MacroH2A restricts melanoma progression via inhibition of chemokine expression in cancer-associated fibroblasts [RNA-seq]
The histone variant macroH2A has been implicated as a tumor suppressor in melanoma and other cancers, yet its role in the tumor microenvironment remains unappreciated. Here we show that mice constitut
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The impact of CXCL5 overexpression on the primary tumor microenvironment of B16F1 melanomas. Mus musculus
CXCL5, a strong neutrophil-chemoattractant, has been reportet to be expressed in different cancer entities with diverse outcomes in disease progression. Contradictory outcome in disease progression in
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Melanoma cells repress Desmoglein 1 in keratinocytes to promote tumor cell migration
Melanoma is an aggressive cancer typically arising from transformation of melanocytes residing in the basal layer of the epidermis, where they are in direct contact with surrounding keratinocytes. The
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