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Dux promotes metabolism-lactylation-MET cascaded network during early iPSC reprogramming with Brg1 as the histone lactylation reader

NIAID Data Ecosystem2026-05-01 收录

iPSC重编程

组蛋白乳酰化

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE251642 数据链接链接失效反馈

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资源简介：

This SuperSeries is composed of the SubSeries listed below. Refer to individual Series

应用场景：

创建时间：

2024-03-02

干细胞多能性调控

iPSC重编程

Polycomb group (PcG) proteins comprise a large group of evolutionary conserved factors with essential roles for embryonic development and adult stem cell function. PcG proteins constitute two main mul

NIAID Data Ecosystem140

AllProbes_AllReplicates.xls

iPSC重编程

基因表达谱分析

Gene expression profiling during iPS reprogramming of C/EBPa-pulsed B cells into iPS cells. The file contains normalized data for all the probes and replicates.

Figshare2014-05-22 更新70

The Nucleolar Remodeling is Required for the of Mouse Fibroblasts Reprogramming to iPSC [ATAC-Seq]

iPSC重编程

核仁重塑

The nucleolus is a membraneless organelle responsible for ribosome biogenesis, perinuclear heterochromatin formation, and genome stability regulation. However, how cell fate decision occurs, including

NIAID Data Ecosystem50

Functionally distinct roles for TET-oxidized 5-methylcytosine bases in somatic reprogramming to pluripotency [RNA-Seq]

iPSC重编程

DNA去甲基化机制

Active DNA demethylation via Ten-eleven Translocation (TET) family enzymes is essential for epigenetic reprogramming in cell state transitions. TET enzymes catalyze up to three successive oxidations o

NIAID Data Ecosystem80

High-throughput sequencing of sequentially reprogrammed iPS cells reveals key epigenetic modifications correlated with reduced pluripotency of iPS cells [MeDIP-seq]

iPSC重编程

表观遗传修饰

Full pluripotency of induced pluripotent stem (iPS) cells has been determined as viable all-iPS mice can be generated through tetraploid complementation. Subsequently, activation of imprinted Dlk-Dio3

NIAID Data Ecosystem60

Dux promotes metabolism-lactylation-MET cascaded network during early iPSC reprogramming with Brg1 as the histone lactylation reader

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