Mouse Transcriptome sequncing. Mus musculus

NIAID Data Ecosystem2026-03-10 收录

β细胞增殖

mTORC1信号通路

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https://www.ncbi.nlm.nih.gov/bioproject/PRJNA488523 数据链接链接失效反馈

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资源简介：

This study was aimed at identifing gene regulating network regarding how mTORC1 signaling controls mouse islet beta cell proliferation during embryonic and neonatal period.

创建时间：

2018-08-30

Identification of direct transcriptional targets of Nfatc2 that promote β-cell proliferation in human islets (ATAC-seq)

β细胞增殖

植物转录因子靶点鉴定

The transcription factor Nfatc2 is a potent β-cell mitogen in mouse and human islets, however, the direct genomic targets that mediate the mitogenic effects have not been identified. We expressed a co

NIAID Data Ecosystem150

Gene expression data from control and REPTOR (=CG13624) KO male adults

基因表达调控

mTORC1信号通路

The aim was to identify genes whose transcription is induced or repressed by REPTOR (=CG13624) KO in Drosophila melanogaster male adults. Data are part of the manuscript REPTOR and REPTOR-BP regulate

NIAID Data Ecosystem40

The effect of TRPM7 kinase inactivation on expression levels of the genes involved in insulin production and cell cycle regulation in pancreatic islets. The effect of TRPM7 kinase inactivation on expression levels of the genes involved in insulin production and cell cycle regulation in pancreatic islets

胰岛素分泌调节

β细胞增殖

To investigate the function of TRPM7 kinase in the regulation of insulin production and beta cell proliferation, we used a mouse model harboring a single point mutation at the active site of the enzym

NIAID Data Ecosystem30

Decrease in Tripartite Motif Containing 24 suppresses hypoxia-induced proliferation and migration of pulmonary arterial smooth muscle cells via the AKT/mammalian target of rapamycin complex 1 pathway

高压病理

mTORC1信号通路

Tripartite Motif Containing 24 (TRIM24) is an oncogenic protein and promotes proliferation in several cancer cell lines. Nevertheless, the role of TRIM24 in proliferation and migration of pulmonary ar

NIAID Data Ecosystem40

Mus musculus Raw sequence reads. Mus musculus

β细胞增殖

转录组学分析

We have constructed a model to induce the proliferation of pancreatic beta cells by a short-term high-fat diet and attempted to explore the underlying mechanism by transcriptomics.

NIAID Data Ecosystem30

Mouse Transcriptome sequncing. Mus musculus

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