Gut Microbiome Raw 16S Sequencing Reads - SIMBA Capsule

The small intestine (SI) microbiome is increasingly implicated in both functional gastrointestinal (GI) disorders and a wide range of systemic diseases. However, owing to limitations of traditional GI sampling approaches, the SI remains challenging to directly access on a large scale. To this end the Small Intestinal MicroBiome Aspiration Capsule (SIMBA) was developed as an effective means for sampling SI luminal content. This collection contains paired-end V4 amplicon sequencing datasets of SIMBA SI, paired fecal, endoscopic aspirate, and saliva samples collected from an observational study of 30 participants for benchmarking purposes.