scRNA-Seq analysis of Trim28-deleted NPp53 mouse prostate tissue
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE199015
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资源简介：
The Tripartite motif-containing 28 (TRIM28) transcription factor is upregulated in high-grade prostate cancers and was recently proposed as a therapeutic target for castration-resistant prostate cancers. To study the role of TRIM28 in prostate cancer progression in vivo, we used a genetically engineered mouse model, combining prostate-specific Trim28 inactivation with inactivation of Trp53 and Pten. We analyzed the prostates using single cell RNA-Seq. scRNA-Seq expression profiles from NPp53 (Pten;Tp53 deleted) and NPp53T (Pten;Tp53; Trim28 deleted) mouse prostates with EYFP for lineage tracing
创建时间：
2023-03-09
