Crystal Structure of the bromodomain of human BAZ2B in complex with 1-[7-(morpholin-4-yl)-1-(pyridin-2-yl)indolizin-3-yl]ethanone (GSK2834113A)

Protein Data Bank Japan2023-09-20 更新2026-03-21 收录

下载链接：

https://pdbj.org/mine/summary/4ir4

下载链接

链接失效反馈

官方服务：

资源简介：

Crystal Structure of the bromodomain of human BAZ2B in complex with 1-[7-(morpholin-4-yl)-1-(pyridin-2-yl)indolizin-3-yl]ethanone (GSK2834113A) Descriptor: 1,2-ETHANEDIOL, 1-[7-(morpholin-4-yl)-1-(pyridin-2-yl)indolizin-3-yl]ethanone, Bromodomain adjacent to zinc finger domain protein 2B Authors: Chaikuad, A, Felletar, I, Chung, C.W, Drewry, D, Chen, P, Filippakopoulos, P, Fedorov, O, Krojer, T, von Delft, F, Arrowsmith, C.H, Edwards, A.M, Bountra, C, Knapp, S, Structural Genomics Consortium (SGC) Deposit date: 2013-01-14 Release date: 2013-01-23 Last modified: 2023-09-20 Method: X-RAY DIFFRACTION (2.05 Å) Cite: Discovery and Characterization of GSK2801, a Selective Chemical Probe for the Bromodomains BAZ2A and BAZ2B. J.Med.Chem., 59, 2016

人源BAZ2B溴结构域（bromodomain）与1-[7-(4-吗啉基)-1-(2-吡啶基)中氮茚-3-基]乙酮（GSK2834113A）复合物的晶体结构 Descriptor: 1,2-乙二醇、1-[7-(4-吗啉基)-1-(2-吡啶基)中氮茚-3-基]乙酮、锌指结构域邻近溴结构域蛋白2B（Bromodomain adjacent to zinc finger domain protein 2B） Authors: Chaikuad, A、Felletar, I、Chung, C.W、Drewry, D、Chen, P、Filippakopoulos, P、Fedorov, O、Krojer, T、von Delft, F、Arrowsmith, C.H、Edwards, A.M、Bountra, C、Knapp, S，以及结构基因组学联合会（Structural Genomics Consortium, SGC） Deposit date: 2013-01-14 Release date: 2013-01-23 Last modified: 2023-09-20 Method: X射线衍射（X-RAY DIFFRACTION，2.05埃） Cite: 《GSK2801的发现与表征：针对BAZ2A与BAZ2B溴结构域的选择性化学探针》，发表于《药物化学杂志（J.Med.Chem.）》，第59卷，2016年

创建时间：

2013-01-14