Dataset includes 54 male and female patients 18 years or over with a histological or cytological diagnosis of malignant pleural mesothelioma (MPM) that was not amendable to curative surgical resectio
Malignant pleural mesothelioma (MPM) arises from mesothelial cells lining the pleural cavity of asbestos-exposed individuals and rapidly leads to death. MPM harbors loss-of-function mutations in BAP1,
Introduction: Over the past decade, classifications using immune cell infiltration have been applied to many types of tumors; however, mesotheliomas have been less frequently evaluated. Methods: In th
Adverse Outcome Pathway for malignant pleural mesothelioma, known to be initiated by asbestos and carbon nanotubes. This molecular AOP is based on https://aopwiki.org/aops/409
Dose concentration curves showing cell viability (calcein-AM assay) for each single compounds and the AND mixture, and for each cell type. Vertical dotted line: IC50; vertical continuous