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Oleanane-Type Triterpenoids from the Leaves and Twigs of <i>Fatsia polycarpa</i>

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NIAID Data Ecosystem2026-03-07 收录
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Seven new oleanane-type triterpenoids (1–7), named fatsicarpains A–G, and the known compounds 3α-hydroxyolean-11,13(18)-dien-28-oic acid (8) and 3α-hydroxyolean-11-en-28,13β-olide (9) were isolated from the leaves and twigs of Fatsia polycarpa on the basis of bioassay-guided fractionation. The structures of compounds 1–7 were elucidated through spectroscopic analyses and single-crystal X-ray crystallography of 1, 8, and 9. Cytotoxicity against HepG2 2.2.15 and AGS cells and antihepatitis B virus (HBV) and antibacterial activities of 1–9 were also evaluated in vitro.

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2016-02-23
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