Effects of Exercise on Gut Microbiota in Obesity and Type 2 Diabetes: A Systematic Review and Meta-Analysis

The development of metabolic diseases is closely associated with the gut microbiota. While accumulating evidence indicates that exercise can modulate the composition of the gut microbiota, its effects in individuals with obesity and type 2 diabetes (T2D) remain inconsistent. This study aims to systematically evaluate the effects of exercise on the gut microbiota in individuals with obesity and T2D, and to explore the potential optimal exercise regimen.代谢疾病的发生发展与肠道菌群（gut microbiota）密切相关。尽管日益增多的研究证据表明，运动可调控肠道菌群的组成，但运动对肥胖及2型糖尿病（type 2 diabetes, T2D）患者的干预效果仍未达成一致。本研究旨在系统评估运动对肥胖与2型糖尿病患者肠道菌群的影响，并探索潜在的最优运动方案。