Emax and pEC50 values of contractile responses induced by the receptor agonists.

The bronchial segments were isolated from rats that were exposed to fresh air, SHS and SHS + GW5074 (0.5 mg/kg) for 8 weeks. The Emax values represent maximal contraction, the pEC50 values represent negative logarithm of the concentration that produces 50% of the maximal contractile effect. The Emax and pEC50 values from airway contractions were induced by 5-HT, S6c, ET-1, U46619 and carbachol. The values are expressed as the means ± SEM and n refers to the number of rats. The statistical analysis was performed using unpaired student's t-test with Welch's correction. *P**P#P