Increased microbial contamination during In vitro organ cultures from collagen X perinatal lethal mice.

Isolated and cultured lung, liver and spleen from week-3 control (WT), collagen X transgenic and null (Col X Tg + KO, pooled data), and Tg and KO perinatal lethal (Col X severe; pooled data) mice reveal increased microbial contamination in perinatal lethal samples. Percent contamination was determined as number of wells contaminated with either bacteria or fungus after 24 hr culture, over the total number of wells per mice tested (in parenthesis).