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Modular microenvironment components reproduce vascular dynamics de novo in a multi-scale agent-based model: EXACT HEMODYNAMICS

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doi.org2025-03-24 收录
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http://doi.org/10.17632/8k7f7fcg7t.2
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Data and results for `EXACT HEMODYNAMICS` simulations. Simulations of cancerous cells in colony and tissue contexts with pattern and various graph layouts. Each condition is run for 15 days (21600 ticks) with 10 replicates (random seeds 0 - 9). Cancerous cells (max_height x 1.5, meta_pref x 1.5, migra_threshold x 0.5) are introduced to the center of the environment after a 1 day delay. Snapshots are taken every 0.5 days (720 ticks). The data folder contains .tar.xz compressed replicate sets. The data.graph folder contains .tar.xz compressed replicate sets for .GRAPH output. The results folder contains .pkl files of data parsed into arrays. Simulations are labeled as: [context]_[sites]_[layout] - [context] - C = colony context, cancerous cells only - CH = tissue context, cancerous cells and healthy cells - [sites] - PATTERN = site architecture defined by pattern - GRAPH = site architecture defined by graph layout - [layout] - simulations with PATTERN do not have a layout label - Lav = line root graph with one artery and one vein (L11) - Lava = line root graph with two arteries and one vein (L21) - Lvav = line root graph with one artery and two veins (L12) - Sav = single root graph with one artery and one vein (S11) - Savav = single root graph with two arteries and two veins (S22)

本数据集包含针对`精确血流动力学`模拟的数据和结果。该数据集模拟了在群体和组织环境中的癌细胞生长过程,并采用多种图形布局进行展示。每个条件均在15天内(21600个时间步长)进行10次重复实验(随机种子为0至9)。在第1天延迟后,将癌细胞(最大高度为max_height x 1.5,元偏好为meta_pref x 1.5,迁移阈值migra_threshold x 0.5)引入环境中心。每隔0.5天(720个时间步长)进行一次快照。数据文件夹包含以.tar.xz格式压缩的重复实验数据集。数据.graph文件夹包含以.tar.xz格式压缩的重复实验数据集,用于.GRAPH输出。结果文件夹包含解析成数组的数据的.pkl文件。模拟标签为:[环境]_[位置]_[布局] - [环境] - C = 群体环境,仅含癌细胞 - CH = 组织环境,含癌细胞和健康细胞 - [位置] - PATTERN = 由图案定义的场地架构 - GRAPH = 由图形布局定义的场地架构 - [布局] - 采用PATTERN的模拟没有布局标签 - Lav = 具有一条动脉和一条静脉的线性根图(L11) - Lava = 具有两条动脉和一条静脉的线性根图(L21) - Lvav = 具有一条动脉和两条静脉的线性根图(L12) - Sav = 具有一条动脉和一条静脉的单根图(S11) - Savav = 具有两条动脉和两条静脉的单根图(S22)
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