five

Diabetic Peripheral Neuropathy

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NIAID Data Ecosystem2026-05-02 收录
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Background: Diabetes often results in diabetic peripheral neuropathy (DPN), which impairs quality of life, causes pain, and limits movement. While they focus on managing symptoms, conventional therapies can offer not much reduction. Neurodynamic methods, which focus on the movement and function of nerves. This study aimed to evaluate the effectiveness of a neurodynamic approach in improving pain, mobility, and nerve function in the lower limbs of individuals with diabetic peripheral neuropathy (DPN). Methods: This study will be a Randomize Clinical Trial (RCT) of diabetes patients with peripheral neuropathy. Total 84 participants were randomly allocated to neurodynamic technique and conventional therapy group equally as per inclusion and exclusion criteria. These subjects will be distributed on random basis to any one of two group (n=42). Outcome measures were neuropathy severity, pain and Neuro-quality of life. Neurodynamic mobilization and foot exercises was given to group A(experimental group) ,Sham neurodynamic mobilization and foot exercises was given to group B(control group) , TENS and foot exercises will be given to both group at four weeks and three session(30min). All three groups will also receive education regarding glycemic control and foot care. A group of participants with DPN underwent a structured neurodynamic therapy program for four weeks. Key outcomes, including pain levels, nerve function, and mobility, were measured before and after the intervention using validated assessment tools. Perspectives: This study suggest that neurodynamic technique, foot mobilization exercise and transcutaneous electrotherapy will effective in reducing the pain associated with peripheral neuropathy.
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2025-01-22
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