Unadjusted endophenotypes for schizophrenia subjects and unaffected siblings.
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Abbreviations: CNB, Computerized Neurocognitive Battery; CPT-IP, Continuous Performance Test, Identical Pairs version; CVLT, California Verbal Learning Test; DS-CPT, Degraded Stimulus Continuous Performance Test; LNS, Letter-Number Span; PPI, prepulse inhibition.aProportion correct out of a maximum of 60 trials.bPrepulse inhibition using 60 msec pulses.100 × [1 − (magnitude of startle to pulse preceded by prepulse/magnitude of startle to pulse without a preceding prepulse)].cOverall signal/noise discrimination (d′).dThree-digit d′.eFour-digit d′.fAfter each sequence, the participant is asked to recall the numbers and letters in the same exact order, with no reordering of the stimuli. The number of digits and letters increases by one on each trial, from one up to a maximum length of 8 stimuli. Three sequences of the same length are presented during each trial. The test is discontinued when the subject fails three consecutive sequences of the same length. The score is the total number of correctly recalled sequences.gAfter each sequence, the participant is asked to repeat the numbers in ascending order first and then the letters in alphabetical order.hTrials 1–5 Free Recall Correct.iTotal semantic clustering scores on trials 1–5.jThe number of correct responses standardized to a z-score based on the COGS community control subjects.
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2015-12-02



