ADVANCES IN REGIONAL CHEMOTHERAPY: A TARGETED APPROACH TO CANCER TREATMENT
收藏DataCite Commons2026-05-03 更新2026-05-07 收录
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https://zenodo.org/doi/10.5281/zenodo.20002408
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资源简介：
Regional chemotherapy delivers cytotoxic agents directly to tumor-bearing regions while minimizing systemic exposure. This review examines HIPEC, HAI, TACE, PIPAC, and ILP modalities. Achieving locoregional drug concentrations 15–20× higher than systemic administration, these techniques enhance tumoricidal efficacy with reduced toxicity. Recent 2026 advances include molecular profiling integration, nanoparticle delivery, and combination immunotherapy. Clinical evidence demonstrates significant survival benefits in colorectal peritoneal metastases, hepatocellular carcinoma, and melanoma.
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Zenodo
创建时间：
2026-05-03
