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Altered Expression of Intraflagellar Transport Genes is Associated with Short Cilia in Smoking and COPD

ChEBI2014-02-03 更新2026-07-21 收录

纤毛功能障碍机制

COPD分子病理

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https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-GEOD-43939 数据链接链接失效反馈

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Altered Expression of Intraflagellar Transport Genes is Associated with Short Cilia in Smoking and COPD

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创建时间：

2014-02-03

癌症生物标志物

COPD分子病理

The objective is to establish robust transcriptional regulation differences between lung cancer (LC) and chronic obstructive pulmonary disease (COPD) by studying miRNA and concurrent transcriptional p

NIAID Data Ecosystem50

Additional file 2 of Distinct COPD subtypes in former smokers revealed by gene network perturbation analysis

COPD分子病理

临床特征关联分析

Additional file 2: Table S1. Excel file containing this table is attached. Clinical characteristics of COPD participants vary across clusters. The variables are sorted by descending significance. P-va

Figshare2024-08-13 更新40

Roflumilast N-Oxide Prevents Cytokine Secretion Induced by Cigarette Smoke Combined with LPS through JAK/STAT and ERK1/2 Inhibition in Airway Epithelial Cells

COPD分子病理

气道炎症药物靶点

Cigarette smoke is a major cause of chronic obstructive pulmonary disease (COPD). Airway epithelial cells and macrophages are the first defense cells against cigarette smoke and these cells are an imp

NIAID Data Ecosystem40

Altered regulation and expression of genes by BET family of proteins in alveolar macrophages from COPD patients

COPD分子病理

BET蛋白

BET proteins (BRD2, BRD3, BRDT and BRD4) belong to the family of bromodomain containing proteins, which form a class of transcriptional co-regulators.Â BET proteins bind to acetylated lysines in the

NIAID Data Ecosystem40

miRNA changes in mild and moderate emphysema correlate with target gene expression in vivo and in vitro [target gene expression data]

COPD分子病理

miRNA靶标验证

To define the role of microRNAs and their mRNA targets in emphysema severity in COPD patients. We performed Agilent human miRNA oligo arrays (8x15K array, Part No. G4470A, Agilent Technologies) based

NIAID Data Ecosystem40

Altered Expression of Intraflagellar Transport Genes is Associated with Short Cilia in Smoking and COPD

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