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Gut-microbiome changes in response to Phenylketonuria can be partially restored by liberalizing Phe-restriction
Phenylketonuria is a metabolic disorder caused by a hepatic enzyme deficiency causing high blood and brain levels of the amino acid Phenylalanine, leading to severe cognitive and psychological deficit
NIAID Data Ecosystem120
Antibiotics-induced alterations of gut microbiome emancipate the insulin resistance in iNOS knockout mice
Inducible nitric oxide synthase (iNOS), a mediator of inflammation, has emerged as a metabolic regulator. Recent studies demonstrated metabolic perturbations in iNOS-/- mice highlighting importance of
NIAID Data Ecosystem60
Table_2_Maternal Exposure to Non-nutritive Sweeteners Impacts Progeny’s Metabolism and Microbiome.XLSX
Non-nutritive sweeteners (NNS) are marketed as sugar alternatives providing sweet taste with few or no calories. Yet their consumption has been linked to metabolic dysfunction and changes in the gut m
NIAID Data Ecosystem30
Associations of circulating metabolites with childhood allergy and common allergic diseases: a Mendelian randomization study
Asthma and other allergic diseases, driven by immune dysregulation, pose a significant global health burden. While observational and experimental studies suggest a link between metabolites and allergi
Figshare2025-12-15 更新50
