Gold Catalysis: Regio- and Stereoselective Total Synthesis of Xyloketals D and G and the Related Natural Product Alboatrin
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A new and efficient one-pot desilylation–gold-catalyzed cycloisomerization of alkynes containing a silyl-protected phenolic −OH and a free alcoholic −OH unit leads selectively to the formation of tetrahydrofuranobenzopyran ring system. This approach has been used for the regio- and stereoselective synthesis of xyloketal D, xyloketal G, and the related natural product alboatrin.
创建时间:
2016-02-19



