Table S1 - Mouse Background Strain Profoundly Influences Paneth Cell Function and Intestinal Microbial Composition

C57BL/6 and 129/SvEv mice express distinct enteric α-defensins at the peptide-level. Observed mass-to-charge (m/z) values of prominent, software-indicated mass peaks found within the expected cryptdin mass range (2499.0 to 4518.0 m/z) are tabulated in correspondence to the gel bands labeled in Fig. 3B. The observed m/z values are listed in increasing value and are classified as being major or minor based on whether the signal intensities of the mass peaks were greater or lesser than 50% of signal intensity relative to baseline, respectively. Determination of the cryptdin identity of individual m/z values was assisted by a comparison of the observed m/z values with the calculated m/z values of all purified and transcript- and gene-predicted cryptdin peptides based upon their oxidized, singly-protonated forms. Matches of m/z values with greater than 99.8% identity or with mass differences less than 5 Da were deemed sufficient for individual identification of mass peaks. Percent identity of m/z values was calculated from the quotient of the lesser over the greater m/z values of matched pairs. The label vDefa24 is used for various non-identical masses since there are multiple Defa24 variant transcripts that have yet to acquire unambiguous identifiers. To indicate a non-identifiable m/z value, the label N.I. was used. Note that the identification of Defa20 was extrapolated by the presence of an m/z value that was more than 98% identical to the predicted m/z value of the doubly-protonated form of oxidized Defa20, since mass spectrometric analysis was performed outside the mass range of its predicted, singly-protonated-based m/z value (4950.69). (DOC)