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Available therapeutics for HAT.
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创建时间：
2012-09-27
相关数据集
Isometamidium chloride and homidium chloride fail to cure mice infected with Ethiopian Trypanosoma evansi type A and B
BackgroundTrypanosoma evansi is mechanically transmitted by biting flies and affects camels, equines, and other domestic and wild animals in which it causes a disease called surra. At least two types
Figshare2018-09-24 更新90
Structure of TbAQP2 in complex with anti-trypanosomatid drug melarsoprol
Structure of TbAQP2 in complex with anti-trypanosomatid drug melarsoprol
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Crystal Structure of Trypanosome cruzi farnesyl diphosphate synthase in complex with [2-(cyclohexylamino)ethane-1,1-diyl]bisphosphonic acid and Mg2+
Crystal Structure of Trypanosome cruzi farnesyl diphosphate synthase in complex with [2-(cyclohexylamino)ethane-1,1-diyl]bisphosphonic acid and Mg2+ Descriptor: 3-METHYLBUT-3-ENYL TRIHYDROGEN DIPHOSPH
Protein Data Bank Japan2024-10-30 更新60
Enhancement of Benzothiazoles as Pteridine Reductase‑1 Inhibitors for the Treatment of Trypanosomatidic Infections
2-Amino-benzo[d]thiazole was identified as a new scaffold for the development of improved pteridine reductase-1 (PTR1) inhibitors and anti-trypanosomatidic agents. Molecular docking and crystallogra
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Efficacy of intramuscular DB829 against second stage T. b. rhodesiense infection in vervet monkeys.
Key: DPI, days post-infection; P, parasitaemia; CSF, cerebrospinal fluid; EoT, end of treatment; LDD, last drug dose; F, female; M, male; Neg, Negative; WD (91), withdrawn 91 days post-LDD; a, median
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