Spearman partial correlation coefficients (adjusted for age) between HMW adiponectin and various metabolic risk factors in metabolically healthy and unhealthy subjects.

PHDL – high-density lipoprotein, BMI– body mass index, HOMA-IR – homeostasis model of insulin resistance, OGTT – oral glucose tolerance test.Healthy – subjects without impaired glucose regulation, hypertension (blood pressure ≥130/80 mmHg), dyslipidaemia (triglycerides ≥1.7 mmol/L or HDLUnhealthy – subjects with impaired glucose regulation and/or hypertension and/or dyslipidaemia and/or insulin resistance.Insulin resistance – was defined as the upper quartile of HOMA-IR in the whole study group (exempting subjects with previously known diabetes mellitus), the threshold of which in whole study group was found to be 1.92 (2.04 and 1.82 for men and women, resp.).