Structure of the Complement classical and lectin pathway C3 convertase in complex with substrate C3
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Structure of the Complement classical and lectin pathway C3 convertase in complex with substrate C3 Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose, Anti-C4b nanobody B12, Complement C2, ... Authors: De la O Becerra, K.I, Brondijk, T.H.C, Gros, P. Deposit date: 2025-03-19 Release date: 2025-12-24 Last modified: 2026-03-04 Method: ELECTRON MICROSCOPY (3.5 Å) Cite: Structural insights into C3 convertase activity of the classical pathway of complement. Nat Commun, 17, 2025
补体经典与凝集素途径C3转化酶结合底物C3的复合物结构
组分描述:2-乙酰氨基-2-脱氧-β-D-吡喃葡萄糖(2-acetamido-2-deoxy-beta-D-glucopyranose)、抗C4b纳米抗体B12(Anti-C4b nanobody B12)、补体C2(Complement C2)等
作者:德·拉·奥·贝塞拉(De la O Becerra), K.I.;布隆迪克(Brondijk), T.H.C.;格罗(Gros), P.
存档日期:2025-03-19
发布日期:2025-12-24
最后修改日期:2026-03-04
实验方法:电子显微镜(分辨率3.5埃)
引用文献:《补体经典途径C3转化酶活性的结构解析》,《自然-通讯》(*Nature Communications*,缩写*Nat Commun*),第17卷,2025年
创建时间:
2025-03-19



