Human Smoothened Receptor structure in complex with cyclopamine
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Human Smoothened Receptor structure in complex with cyclopamine Descriptor: Cyclopamine, Smoothened homolog/Soluble cytochrome b562 chimeric protein Authors: Wang, C, Weierstall, U, James, D, White, T.A, Wang, D, Liu, W, Spence, J.C.H, Doak, R.B, Nelson, G, Fromme, P, Fromme, R, Grotjohann, I, Kupitz, C, Zatsepin, N.A, Liu, H, Basu, S, Wacker, D, Han, G.W, Katritch, V, Boutet, S, Messerschmidt, M, Willams, G.J, Koglin, J.E, Seibert, M.M, Klinker, M, Gati, C, Shoeman, R.L, Barty, A, Chapman, H.N, Kirian, R.A, Beyerlein, K.R, Stevens, R.C, Li, D, Shah, S.T.A, Howe, N, Caffrey, M, Cherezov, V, GPCR Network (GPCR) Deposit date: 2014-01-02 Release date: 2014-03-05 Last modified: 2024-10-16 Method: X-RAY DIFFRACTION (3.204 Å) Cite: Lipidic cubic phase injector facilitates membrane protein serial femtosecond crystallography. Nat Commun, 5, 2014
与环巴胺(cyclopamine)结合的人源smoothened受体(Smoothened Receptor)复合物结构
描述物:环巴胺(cyclopamine)、smoothened同源蛋白/可溶性细胞色素b562嵌合蛋白
作者:Wang, C、Weierstall, U、James, D、White, T.A、Wang, D、Liu, W、Spence, J.C.H、Doak, R.B、Nelson, G、Fromme, P、Fromme, R、Grotjohann, I、Kupitz, C、Zatsepin, N.A、Liu, H、Basu, S、Wacker, D、Han, G.W、Katritch, V、Boutet, S、Messerschmidt, M、Willams, G.J、Koglin, J.E、Seibert, M.M、Klinker, M、Gati, C、Shoeman, R.L、Barty, A、Chapman, H.N、Kirian, R.A、Beyerlein, K.R、Stevens, R.C、Li, D、Shah, S.T.A、Howe, N、Caffrey, M、Cherezov, V、GPCR研究网络(GPCR Network, GPCR)
提交日期:2014-01-02
发布日期:2014-03-05
最后修改日期:2024-10-16
实验方法:X射线衍射(X-RAY DIFFRACTION),分辨率3.204埃
引用文献:《脂立方相注射装置助力膜蛋白串行飞秒晶体学》,《自然-通讯(Nature Communications)》,第5卷,2014年
创建时间:
2014-01-02



