Cryo-EM structure of the WB4-24-bound hGLP-1R-Gs complex
收藏Protein Data Bank Japan2024-10-16 更新2026-03-28 收录
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Cryo-EM structure of the WB4-24-bound hGLP-1R-Gs complex Descriptor: 2,4-bis(3-methoxy-4-thiophen-2-ylcarbonyloxy-phenyl)-1,3-bis[[4-(2-methylpropanoylamino)phenyl]carbonylamino]cyclobutane-1,3-dicarboxylic acid, Glucagon-like peptide 1 receptor, Guanine nucleotide-binding protein G(I)/G(S)/G(O) subunit gamma-2, ... Authors: Cong, Z.T, Zhou, Q.T, Li, Y, Chen, L.N, Zhang, Z.C, Liang, A.Y, Liu, Q, Wu, X.Y, Dai, A.T, Xia, T, Wu, W, Zhang, Y, Yang, D.H, Wang, M.W. Deposit date: 2022-03-14 Release date: 2022-06-29 Last modified: 2024-10-16 Method: ELECTRON MICROSCOPY (3.09 Å) Cite: Structural basis of peptidomimetic agonism revealed by small- molecule GLP-1R agonists Boc5 and WB4-24. Proc.Natl.Acad.Sci.USA, 119, 2022
创建时间：
2022-03-14
