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Reduction of PRC2 activity supports survival of TNBC cancer cells to cytotoxic treatments

ChEBI2021-11-30 更新2026-07-12 收录

三阴性乳腺癌耐药性

表观遗传调控

数据链接：

https://www.ebi.ac.uk/biostudies/ArrayExpress/studies/E-MTAB-9547 数据链接链接失效反馈

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Reduction of PRC2 activity supports survival of TNBC cancer cells to cytotoxic treatments

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创建时间：

2021-11-30

表观遗传调控

甲基化反应机制

DNA methylation at the 5-position of cytosine (5mC) is a crucial epigenetic mark in regulating biological processes including gene silencing, gene imprinting, and X chromosome inactivation. It has lon

NIAID Data Ecosystem00

A TAD boundary is preserved upon deletion of the CTCF-rich Firre locus [RNA-Seq, HiC_C2C12, ChIP-Seq]

基因组三维结构

表观遗传调控

The binding of the transcriptional regulator CTCF to the genome has been implicated in the formation of topologically associated domains (TADs). However, the general mechanisms of folding the genome i

NIAID Data Ecosystem00

The RNA Silencing Enzyme RNA Polymerase V Is Required for Plant Immunity

植物免疫机制

表观遗传调控

RNA–directed DNA methylation (RdDM) is an epigenetic control mechanism driven by small interfering RNAs (siRNAs) that influence gene function. In plants, little is known of the involvement of the RdDM

Figshare2016-01-18 更新00

Epigenetic gene regulation during astrocyte development

胶质细胞发育

表观遗传调控

Numerous literatures report similar time points are important in astrocyte development and transition from neurogenesis to gliogenesis. However, these developmental time points have not been studied i

NIAID Data Ecosystem00

H3 Acetylation and H2A.Z Levels Interplay to Regulate Gene Expression and Plant Development

表观遗传调控

发育分子机制

H2A.Z is a conserved histone variant that plays essential roles in various DNA-templated processes across eukaryotes. H2A.Z and histone post-translational modifications (PTMs) exert a bidirectional an

NIAID Data Ecosystem00

Reduction of PRC2 activity supports survival of TNBC cancer cells to cytotoxic treatments

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