Transcriptomic Profiling on Intestine of Diabetic and Septic Mice [RNA-seq]

Sepsis is a severe clinical syndrome related to an exaggerated host immune response to infection as well as systematic inflammation and serious tissue damage. Sepsis-induced intestine injury is one of the most frequent and serious complications of sepsis. This study aimed to identify new mechanisms in sepsis-induced intestine injury through transcriptome profiling (RNA-seq). Overall design: Mice were randomly divided into 3 groups: wt-CLP group (n=2), db-CLP group (n=2), db-Sham group (n=2).