Modelling of drug action.
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Va, IIa, IXa, Xa and XIa denote activated coagulation factors. ATIII, antithrombin; BAY59-7939, rivaroxaban; fu, fraction unbound; Hep, heparin (here parameterized as enoxaparin); on, kon, association rate constant; mIIa, meizothrombin; Tm, thrombomodulin; Xim, ximelagatran active metabolite (melagatran).
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2015-12-02



