microRNAs are abundant and stable in Platelet-rich fibrin and other autologous blood products of canines

Regenerative properties and clinical adaptability of platelet-rich fibrin have been discussed in previous human research, but information about its composition in animals is lacking. It has been reported that microRNAs play an essential role in wound healing and inflammatory process. In this study, we reported the presence of various microRNAs in the platelet-rich fibrin and other autologous blood products of canines, including confirmed stability properties. We believe this research might be a step forward in understanding the regenerative mechanisms and adapting new therapy methods that can be used in humans and animals based on One Health principles.