Tinagl1 Suppresses Triple-negative Breast Cancer Progression by Simultaneously Targeting Integrin/FAK and EGFR Signaling Pathways

Enforced Tinagl1 expression in lung metastatic MDA-MB231 subline LM2 cells suppresses lung metastasis by inhibiting EGFR and Integrin/FAK activation Breast cancer cell line with Tinagl1 or empty vector were injected into NSG female mice intravenously. Lung metastatic lesions were dissected for microarray analysis