We report a novel role of ASXL1 protein in altering epigentic profile of osteoclast. ASXL1 is an ETP protein that bind to polycomb repressive complex. We asked if ASXL1 regulates osteoclast different
Genes whose histone modification pattern changes from bivalent to monovalent during osteoclastogenesis and with NFATc1 binding near the transcription start site.
Comparaison of genes expression between bone marrow derived macrophages and osteoclasts in C57BL/6J mice Overall design: 2 samples with 3 mice per sample.
