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Analysis of Fusobacterium nucleatum Driven Modulation of c-Myc Pathways in Oral Carcinogenesis

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Figshare2025-12-15 更新2026-04-28 收录
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https://figshare.com/articles/dataset/Analysis_of_i_Fusobacterium_nucleatum_i_Driven_Modulation_of_c-Myc_Pathways_in_Oral_Carcinogenesis/30885599
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Objective: To evaluate the association between Fusobacterium nucleatum and c-Myc expression in Oral Potentially Malignant Disorders (OPMDs) and Oral Squamous Cell Carcinoma (OSCC), and to explore its potential role in oral carcinogenesis. Materials and Methods: A total of 32 histopathologically confirmed cases (18 OPMDs, 14 OSCC) were analysed. Anaerobic culture and PCR were used to detect F. nucleatum. Immunohistochemistry (IHC) was performed to assess c-Myc expression. Statistical analysis was conducted using Mann-Whitney and Chi-square tests, with p
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2025-12-15
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