Assessment of the role of the BCRs in transgenic models of chronic lymphocytic leukemia

we evaluated the capacity of different types of antigen/BCR interactions to induce leukemia in a transgenic mouse model of CLL Key words; B-cell antigen receptor (BCR), chronic lymphocytic leukaemia (CLL), T-cell leukemia (TCL) GEP analysis of 7 leukemias with an anti-Sm BCR and 9 leukemias with an anti-PtC BCR