Disruption of actin dynamics reduces KSHV infectivity at low MOI but not high MOI.
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HUVEC were infected with KSHV at a high MOI (10) and a low MOI (2). The effects of actin cytoskeleton-disrupting agents cytochalasin D at 2 µg/ml and jasplakinolide at 1 µM on the average number of viral particles per nuclei (A), and viral infectivity based on the percentage of nuclei containing at least one viral particle (B) or the percentage of LANA-positive cells (C) were examined.
创建时间：
2009-07-10
