Quant-seq analysis of differential polyadenylation site usages in caused by different Pol II mutants with slow elongation rates in Flp-In-293 cells and dual inhibition of CDK12 and CDK13 by THZ531 HEK293T cells
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https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE141375
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We used 3' RNA-Seq to determine the effects of slow elongating Pol II on polyadenatltion site usages, also the effects of CDK12 and CDK13 inhibition caused by THZ531 on alternative polyadenylation We performed 3’RNA-seq (Quantseq) on Flp-In-293 cells with slow elongating or wild-type a-amanitin resistant Pol II, as well as THZ531/DMSO treated HEK293T cells to compare the the effect of slow elongating Pol II to CDK12 and CDK13 inhibtion.
创建时间:
2020-09-21



