Role of Mcam in breast cancer cell state using a model cell line (Py230) [single cell Multiplex]

Morphological changes suggested cell state switching and scRNASeq profiles were therefore generated to use in downstream comparative transcriptomics analysis and for identification of cell state regulators. Overall design: Py230 cells with LV-shControl vs LV-shMcam cells were isolated from 2D cell culture and analyzed using scRNAseq via chromium 10x protocols Please note that processed data files generated from both GEX and Multiplex samples are linked to the corresponding GEX sample records.