MATLAB code P22 model
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MATLAB code Related to Figure 1: Evolution predicted phage titer and cell count (as PFU/mL and CFU/mL, respectively, in panel D), phage production (as PFU/mL×h in panel E), and percentage of lysogens and non-lysogens (in panel F) based on previously published models describing the infection dynamics of phage λ and its host E. coli (33), but adjusted to the chemostat setup monitored in A-C and fitted with the P22 specific parameters for burst size, latent time, adsorption rate, and spontaneous induction. Model equations and parameters (49, 50) can be found in Fig. S2.
与图1相关的MATLAB代码:本内容基于已发表的描述λ噬菌体(phage λ)及其宿主大肠杆菌(E. coli)感染动态的模型(文献33),可预测噬菌体效价与细胞计数(分别对应图D中的噬菌斑形成单位每毫升(PFU/mL)和菌落形成单位每毫升(CFU/mL))、噬菌体增殖量(以图E中的PFU/mL×h为单位)以及溶原菌与非溶原菌的占比(图F);该模型针对图A-C中监测的恒化器培养装置进行了适配调整,并拟合了P22噬菌体专属的裂解量、潜伏期、吸附率及自发诱导率参数。模型方程与参数(文献49、50)详见补充图S2。




