CRYSTAL STRUCTURE OF KRAS-G12C IN COMPLEX WITH COMPOUND 12
收藏Protein Data Bank Japan2024-10-23 更新2026-04-19 收录
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https://pdbj.org/mine/summary/8afc
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CRYSTAL STRUCTURE OF KRAS-G12C IN COMPLEX WITH COMPOUND 12 Descriptor: 2-azanyl-4,4-dimethyl-6,7-dihydro-5~{H}-1-benzothiophene-3-carbonitrile, GTPase KRas, GUANOSINE-5'-DIPHOSPHATE, ... Authors: Boettcher, J, Kessler, D. Deposit date: 2022-07-16 Release date: 2022-11-09 Last modified: 2024-10-23 Method: X-RAY DIFFRACTION (2.41 Å) Cite: Fragment Optimization of Reversible Binding to the Switch II Pocket on KRAS Leads to a Potent, In Vivo Active KRAS G12C Inhibitor. J.Med.Chem., 65, 2022
创建时间：
2022-07-16
