Crystal structure of the carboxyltransferase domain of acetyl-coenzyme A carboxylase in complex with compound 7
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Crystal structure of the carboxyltransferase domain of acetyl-coenzyme A carboxylase in complex with compound 7 Descriptor: 1'-(1H-indazol-7-ylcarbonyl)-6-methylspiro[chromene-2,4'-piperidin]-4(3H)-one, Acetyl-CoA carboxylase, SULFATE ION Authors: Vajdos, F. Deposit date: 2009-04-10 Release date: 2010-04-07 Last modified: 2023-09-06 Method: X-RAY DIFFRACTION (2.43 Å) Cite: Discovery of small molecule isozyme non-specific inhibitors of mammalian acetyl-CoA carboxylase 1 and 2. Bioorg.Med.Chem.Lett., 20, 2010
乙酰辅酶A羧化酶（acetyl-coenzyme A carboxylase）羧基转移酶结构域与化合物7形成复合物的晶体结构。描述信息：1'-(1H-吲唑-7-基羰基)-6-甲基螺[色烯-2,4'-哌啶]-4(3H)-酮、乙酰辅酶A羧化酶、硫酸根离子。作者：Vajdos, F.；沉积日期：2009-04-10；发布日期：2010-04-07；最后修改日期：2023-09-06；实验方法：X射线衍射（X-RAY DIFFRACTION，分辨率2.43 Å）；引用文献：哺乳动物乙酰辅酶A羧化酶1和2的小分子非特异性同工型抑制剂的发现，《Bioorg.Med.Chem.Lett.》，20卷，2010年
创建时间：
2009-04-10
