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Interactome - RNA/DNA Hybrid Interactome Identifies DXH9 as a Molecular Player in Transcriptional Termination and R-Loop-Associated DNA Damage

NIAID Data Ecosystem2026-03-10 收录

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R-loop相关DNA损伤

数据链接：

https://www.omicsdi.org/dataset/pride/PXD002960 数据链接链接失效反馈

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AP-MS from non-crosslinked HeLa cells was carried out as described in the paper.

应用场景：

创建时间：

2018-05-16

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RNA聚合酶功能研究

RNA Polymerase II (RNAPII) transcription termination is regulated by the phosphorylation status of the C-terminal domain (CTD). The phosphatase Rtr1 has been shown to regulate serine 5 phosphorylation

NIAID Data Ecosystem80

Characterization of extended transcripts by RNA-Seq suggests that Rrp6 influences Nrd1-dependent termination

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RNA测序数据分析

Characterization of extended transcripts by RNA-Seq suggests that Rrp6 influences Nrd1-dependent termination

ChEBI2015-04-14 更新50

RNAseq of Bacillus subtilis wildtype and cspB-cspD deletion mutant reveals that the lack of the cold shock proteins CspB and CspD affects the expression of about 20% of all genes. RNAseq of Bacillus subtilis wildtype and cspB-cspD deletion mutant reveals that the lack of the cold shock proteins CspB and CspD affects the expression of about 20% of all genes

冷休克蛋白

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RNAseq of coding RNA in Bacillus subtilis wildtype and deletion strain GP1971 genotype trpC2 ΔcspB::cat ΔcspD::aphA3 using rRNA depleted mRNA and Illumina TruSeq stranded mRNA libraries, sequenced on

NIAID Data Ecosystem30

Pcf11/Spt5 condensates stall RNA polymerase II to facilitate termination and piRNA-guided heterochromatin formation

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piRNA引导异染色质形成

Pcf11/Spt5 condensates stall RNA polymerase II to facilitate termination and piRNA-guided heterochromatin formation

integrated proteome resources60

PP1 PNUTS binds the “restrictor” and dephosphorylates pol II CTD Ser5 to stimulate RNA pol II transcription termination [eNET-seq]

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RNA聚合酶转录

The restrictor complex, WDR82/ZC3H4, is the major termination factor for antisense transcription from bidirectional promoters, but its mechanism of action is poorly understood. We report that the PP1

NIAID Data Ecosystem30

Interactome - RNA/DNA Hybrid Interactome Identifies DXH9 as a Molecular Player in Transcriptional Termination and R-Loop-Associated DNA Damage

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