AACDB
收藏资源简介:
The AACDB (Antibody-Antigen Complex Database) comprises entries obtained from the PDB database, excluding predictive structures. The antibody and antigen information underwent thorough manual verification by cross-referencing with the original literature. Notably, AACDB provides detailed information on interacting residues using two methods (ΔSASA and distance), facilitating the identification of paratopes and epitopes. In summary, AACDB offers a user-friendly interface for convenient querying, manipulation, browsing, and visualization of comprehensive information about antibody-antigen complexes. It also offers customized datasets to cater to specific research requirements.
抗体-抗原复合物数据库(Antibody-Antigen Complex Database,以下简称AACDB)收录了源自PDB数据库(Protein Data Bank)的条目,且剔除了所有预测得到的结构。该数据库中的抗体与抗原信息均经过严格的人工核验,核验方式为与原始文献进行交叉比对。值得注意的是,AACDB提供了基于溶剂可及表面积变化量(ΔSASA)与距离法两种方法得到的相互作用残基详细信息,可助力互补位(paratope)与表位(epitope)的识别工作。综上,AACDB配备了操作友好的用户界面,可便捷实现抗体-抗原复合物相关全面信息的查询、处理、浏览与可视化。同时,该数据库还可提供定制化数据集,以满足特定科研需求。




