Crystal structure of the large fragment of DNA polymerase I from Thermus Aquaticus in an open binary complex with dNaM as templating nucleobase

Crystal structure of the large fragment of DNA polymerase I from Thermus Aquaticus in an open binary complex with dNaM as templating nucleobase Descriptor: (5'-D(*AP*AP*AP*(BMN)P*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3'), (5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3'), DNA polymerase I, ... Authors: Betz, K, Diederichs, K, Marx, A. Deposit date: 2011-07-18 Release date: 2012-06-06 Last modified: 2023-09-13 Method: X-RAY DIFFRACTION (1.952 Å) Cite: KlenTaq polymerase replicates unnatural base pairs by inducing a Watson-Crick geometry. Nat.Chem.Biol., 8, 2012

水生嗜热菌（Thermus Aquaticus）来源的DNA聚合酶I大片段与作为模板碱基的dNaM形成开放型二元复合物的晶体结构。描述：(5'-D(*AP*AP*AP*(BMN)P*GP*GP*CP*GP*CP*CP*GP*TP*GP*GP*TP*C)-3')、(5'-D(*GP*AP*CP*CP*AP*CP*GP*GP*CP*GP*CP*(DOC))-3')，DNA聚合酶I…… 作者：贝茨（Betz, K）、迪德里希斯（Diederichs, K）、马克思（Marx, A.）。沉积日期：2011-07-18；发布日期：2012-06-06；最后修改日期：2023-09-13。实验方法：X射线衍射（1.952埃）。引用：《KlenTaq聚合酶通过诱导形成沃森-克里克碱基配对几何构型以复制非天然碱基对》，《自然·化学生物学（Nat.Chem.Biol.）》，第8卷，2012年。