Table_1_Characterizing the supragingival microbiome of healthy pregnant women.xlsx

The ecological characteristics and changes of the supragingival plaque microbial community during pregnancy are poorly understood. This study compared the microbial community characteristics of supragingival plaque in pregnant and non-pregnant women, with the aim of identifying specific microbial lineages and genera that may be associated with pregnancy. Thirty pregnant women were randomly selected from the First Affiliated Hospital of Xinjiang Medical University and divided into groups based on pregnancy trimester: first trimester (group P1, n=10, ≤12 weeks), second trimester (group P2, n=10, 13–27 weeks), and third trimester (group P3, n=10, 28–40 weeks). Ten healthy non-pregnant women (group N) were enrolled as the control group. Supragingival plaque samples of all subjects were collected and oral microbial composition was surveyed using a 16S rRNA gene sequencing approach. Statistical analysis was performed using a nonparametric test. The Chao 1 index of P3 was significantly lower compared with that of N, P1, and P2 (P

关于妊娠期间龈上菌斑微生物群落的生态特征及其变化，目前认识尚显不足。本研究旨在通过比较妊娠女性与非妊娠女性龈上菌斑的微生物群落特征，识别可能与妊娠相关的特定微生物谱系和属。研究从新疆医科大学第一附属医院随机选取了30名妊娠女性，根据妊娠期分为三个组别：孕早期（P1组，n=10，≤12周）、孕中期（P2组，n=10，13-27周）和孕晚期（P3组，n=10，28-40周）。同时，纳入了10名健康非妊娠女性作为对照组（N组）。对所有受试者的龈上菌斑样本进行了收集，并采用16S rRNA基因测序技术对口腔微生物组成进行了调查。统计分析采用非参数检验方法。结果显示，与N组、P1组和P2组相比，P3组的Chao 1指数显著降低（P