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Manipulating the lysine-arginine balance for successful therapy of malignant glioma by targeting lysosomal membrane integrity [II]

NIAID Data Ecosystem2026-05-02 收录

胶质母细胞瘤转录组

溶酶体膜完整性靶向

数据链接：

https://www.ncbi.nlm.nih.gov/geo/query/acc.cgi?acc=GSE230824 数据链接链接失效反馈

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资源简介：

To investigate the role of TFE3 induced the transcriptional alterations of glioblastoma cells Total RNA was extracted from glioblastoma cells

应用场景：

创建时间：

2025-04-11

胶质母细胞瘤转录组

SOX2靶基因调控网络

Overexpression of the transcription factor SRY-related box 2 (SOX2) is characteristic of Glioblastoma (GBM), yet its regulatory network in vivo is poorly understood. Using a human orthotopic tumor mod

NIAID Data Ecosystem70

Differential gene expression upon ADAR3 expression in U87 glioblastoma cells. Differential gene expression upon ADAR3 expression in U87 glioblastoma cells

胶质母细胞瘤转录组

ADAR3差异表达

The genes that are differentially expressed in ADAR3 expressing cells compared to control U87 cells were identified. Overall design: Total RNA from three biological replicates of ADAR3 expressing and

NIAID Data Ecosystem50

RNA sequencing analysis of human glioblastoma cell line U87MG treated with LMO2 overexpression.. RNA sequencing analysis of human glioblastoma cell line U87MG treated with LMO2 overexpression.

胶质母细胞瘤转录组

LMO2基因功能

To understand the changes in the expression of genes in U87MG cells due to LMO2, we analyzed the transcriptome of U87MG cells overexpressing LMO2. As a result, we identify differentially expressed gen

NIAID Data Ecosystem20

Transcriptomic analysis unveils correlations between regulative apoptotic caspases and genes of cholesterol homeostasis in human brain

caspase-2与胆固醇稳态基因关联

胶质母细胞瘤转录组

Caspases are cysteine-proteases with key roles in the execution phase of apoptosis. Additional cellular activities, unrelated to cell death seem to be influenced by these enzymes. Identification of ge

NIAID Data Ecosystem60

Comprehensive transcriptomic profiling of glioblastoma patient-derived primary tumor cell lines using bulk RNA-sequencing

胶质母细胞瘤转录组

GBM分子机制

Glioblastoma multiforme (GBM) is a highly aggressive primary brain cancer with significant transcriptomic heterogeneity among patients. Our study aims to contribute to the field of personalized medici

NIAID Data Ecosystem30

Manipulating the lysine-arginine balance for successful therapy of malignant glioma by targeting lysosomal membrane integrity [II]

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